San Francisco 49ers tight end Jake Tonges catches a 2-yard touchdown pass on a crossing route from quarterback Mac Jones against the Houston Texans.

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. The Texans are -151 money line favorites (risk $151 to win $100),

San Francisco 49ers QB Mac Jones fired a strike to WR Kendrick Bourne, moving the chains with an 18-yard gain vs. the Texans.

San Francisco 49ers wide receiver Jauan Jennings can't hold on to a deep pass attempt from quarterback Mac Jones against the Houston Texans.

The Texans lost to the Seattle Seahawks 27-19 on Monday night even though Anderson scored the first touchdown of his NFL career. Anderson had a strip-sack of quarterback Sam Darnold and recovered the fumble in the end zone.