Even though both English giants are off to a slow start in the Premier League, this is the biggest matchup of Game Week 6. Both Manchester United and Tottenham Hotspurs only have seven points in five games so far and another loss would push them further down in the bottom half of the table.

Hello! Midweek action ramps up on Wednesday with the UEFA Europa League, which steals the European spotlight this week as the league phase begins. I'm Pardeep Cattry with a look-ahead to this season's competition and the competition's opening games.

Manchester United can't afford to fail in the UEFA Europa League, as manager Erik ten Hag looks to impress the new INEOs bosses this season.