Rafał Durasiewicz, co-founder at Acini, and Agnieszka Kowalczyk, senior business analyst at Acini, discuss how the tech firm tackles its talent hurdles ...
ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini
The mammary epithelium of an adult breast is organized into ducts and lobules. The ducts end in a highly branched structure referred to as the terminal ductal lobular unit (TDLU). A TDLU is comprised ...
Our understanding of the mechanisms by which ducts and lobules develop is derived from model organisms and three-dimensional (3D) cell culture models wherein mammalian epithelial cells undergo ...
Acini (alveoli) from mammary tissue of lactating rats were isolated using collagenase and examined in the transmission electron microscope to determine if changes occur in cellular structure and ...
With increasing stages of breast cancer, initially nonmalignant cells making up the acini in the breast become increasingly disorganized and finally metastasize (top). Breast cells cultured in a three ...
Cancer cells in lab cultures have not "forgotten" how to be healthy since they can be guided back into their "normal" growth program by giving them the right cues. Applying compressive force to ...
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