Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what ...

As with most cancers, triple-negative breast cancer (TNBC) cells have abnormal amounts of chromosomes or DNA copy number aberrations (CNAs) in their genomes. A new study used single cell sequencing ...

Chromosomal aberrations, encompassing both structural and numerical chromosome abnormalities, are fundamental indicators of genomic instability with far‐reaching implications for cancer risk. These ...

A research team at The University of Osaka revealed that the loss of heterochromatin can cause a chain reaction leading to ...

Colorectal cancer is one of the most common types of tumor and is responsible for around 10% of cancer-related deaths worldwide. The tumor is particularly dangerous when it forms metastases—i.e.

How do living things evolve? What is the myriad of processes by which generic variations in a population affect organisms' survival and allow reproduction in an ever-changing environment? Why do these ...

Ewing sarcoma develops due to genetic causes that include changes to a person’s DNA and chromosomes. It more often affects teenagers and young adults, males, and white people. The exact cause of Ewing ...

It is crucial in the development of cell and gene therapies to understand the impact of the gene editing process on chromosomal structure. When cells are edited, differentiated, modified, or ...

Genetic testing for chronic myeloid leukemia (CML) can tell doctors if someone has leukemia, what type they may have, and whether treatment is working. The tests look for atypical changes in certain ...

Pregnancy loss may occur in as many as 25% of all pregnancies. Most of these losses occur in the first trimester, and about half are caused by genetic or chromosomal issues. When pregnancy loss occurs ...