Immunotherapy using modified chimeric antigen receptor (CAR) T cells has improved survival rates for pediatric patients with relapsed and recurrent leukemia. However, these therapies are not as ...

Cytokines are secreted proteins critical for immune regulation, cell signaling, and tissue homeostasis. These cells are increasingly recognized as key tools in biomedical research, particularly in ...

The authoritative peer-reviewed source for research, analysis, and advances on the therapeutic role of cytokines and IFNs. Suppressor of Cytokine Signaling (SOCS) 1 is a key negative regulator of ...

Restoring the gut microbiota through fecal microbiota transplantation reversed these effects. The treatment replenished CX3CR1-positive NK cells, reduced lung damage, and improved survival. Targeted ...

Sepsis is a fatal syndrome characterized by life-threatening organ dysfunction originating from a chaotic and unchecked innate immune response to infection. Notably, macrophages are the master ...

Investigators identified 9 cytokines that can distinguish between disease relapse and remission in ANCA-associated vasculitis. Investigators have identified cytokines they believe are involved in the ...

Rather than aligning with classical hematopoietic signaling, the peptide has been theorized to engage selective molecular pathways associated with cellular stress response, immunomodulatory signaling, ...

The approval makes Dupixent the first FDA-approved therapy for allergic fungal rhinosinusitis, supported by Phase III data showing significant improvements in sinus opacification, nasal symptoms, and ...