DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

The goal of gene therapy is to permanently cure hereditary diseases. One of the most promising technologies for this is the ...

What naked mole-rats lack in the looks department they make up for it in longevity, living healthily for nearly four decades.

The INO80 chromatin remodelling complex has various roles in genome maintenance, acting via nucleosome sliding and H2A.Z ...

Researchers at Spain’s CNIO have mapped 20,000 distinct DNA repair “scars,” building the first human REPAIRome. This atlas ...

Tea will be served at 12:45 p.m., immediately preceding the seminar.

A double-strand break (DSB) is a type of DNA damage where both strands of the DNA helix are cut or broken at the same location, causing a complete discontinuity in the DNA molecule. Unrepaired or ...

A day in the life of DNA can be rough. It gets yanked across a dividing cell, zapped by radiation, and assaulted by chemicals. Luckily, cells have developed a complex set of repair mechanisms to ...

Fusion Challenges in Solid Tumors: Shaping the Landscape of Cancer Care in Precision Medicine PALB2 p.675_D777del ND 0.32 Reversion mutation PALB2 p.M723_G741>VFTCFPHLRYYSSLWPSR ND 0.14 Reversion ...