Double-strand breaks (DSBs) can be repaired by several homologous recombination (HR)-mediated pathways, including double-strand break repair (DSBR) and synthesis-dependent strand annealing (SDSA). a | ...

DNA double-strand breaks (DSBs) represent one of the most deleterious forms of genetic damage, arising naturally during cellular replication or as a result of exposure to ionising radiation. The ...

The goal of gene therapy is to permanently cure hereditary diseases. One of the most promising technologies for this is the ...

Zhi “Zack” Zheng is a member of molecular biologist Scott Keeney's lab. Zhi “Zack” Zheng, who is scheduled to receive his PhD from the Gerstner Sloan Kettering Graduate School of Biomedical Sciences ...

Researchers at Spain’s CNIO have mapped 20,000 distinct DNA repair “scars,” building the first human REPAIRome. This atlas ...

Your silver strands might be doing more than showing your age, according to a new study out of the University of Tokyo.

In a study led by the University of Tokyo and published earlier this month in the journal Nature Cell Biology, researchers ...

Going gray is an inevitable, and for many, undesirable, part of aging, but health-wise, it’s no bad thing – it could reflect ...

Throughout life, our cells are constantly exposed to environmental and internal factors that can damage DNA. While such DNA ...

The INO80 chromatin remodelling complex has various roles in genome maintenance, acting via nucleosome sliding and H2A.Z ...

What naked mole-rats lack in the looks department they make up for it in longevity, living healthily for nearly four decades.