An international collaboration steered by David Cortez, Richard N. Armstrong, Ph.D. Chair for Innovation in Biochemistry, explored how cells tolerate DNA damage and genome instability—and they arrived ...

DNA can be more than just a double helix. When four strands are folded into a compact bundle, they form a G-quadruplex (G4). These bundles form in guanine-rich regions across the genome, including ...

I. Robert Lehman, PhD, a foundational biochemist whose research fueled modern molecular biology and biotechnology, died June 15 at his home on the Stanford University campus, surrounded by his family.

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...