Passive diffusion plays an essential role in oral absorption of drugs through the gastrointestinal tract, penetration across the blood-brain barrier to reach Central Nervous System disease targets, ...

Congestive heart failure is a disease state distinguished by the regular presence of both renal and hepatic abnormalities in drug handling. One such abnormality involves flaws in the process of drug ...

A research team has shown how PEGylated polylysine dendrimers, a new type of nano-sized drug delivery system, can be altered to target either the lymphatic system or the bloodstream, which may improve ...

Of 18 original research articles selected for review, only 43.9% met the methodology criteria identified as essential to include in a pharmacokinetics study, reported Brittany Walsh-Reed, PharmD, BCPS ...

Preliminary study shows GLP-1 receptor agonists alter alcohol response, suggesting potential for reducing cravings and ...

To test the efficacy of the patch, the team loaded the EW-MNs with rivastigmine (a drug commonly used to treat Alzheimer's and Parkinson's disease). In animal studies using guinea pigs, the ...

Title: Tenapanor Improves Bowel Movements in Patients with End-Stage Kidney Disease and Mild to Severe Constipation Authors: Steven Fishbane, Suling Zhao, Yang Yang, Susan Edelstein, David M. Spiegel ...

At first glance, Ozempic and Wegovy seem like miracle drugs of the 21st century — a pair of injections that shrink waistlines ...

From the 1980s, therapeutic protein drugs — monoclonal antibodies, proteins, antibody-drug conjugates, bispecific antibodies, etc. — have been widely employed in the treatment of HIV, tumors and other ...