Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the novel coronavirus, causes coronavirus disease 2019 (COVID-19), which is a multisystem disease affecting the respiratory tract. Data ...

The developing thrombus in a living mouse after vessel-wall injury (Panel A) is characterized by the deposition of platelets (red), tissue factor (green), and fibrin (blue). Platelet thrombus ...

The top panel, designed with BioRender.com, illustrates the process of clot formation and lysis, beginning with platelet aggregation and activation of the coagulation cascade, followed by the ...

However, additional thrombin generation and fibrin formation, maturation of the fibrin network, and generation of antifibrinolytic mechanisms that protect the clot from premature degradation occur ...

Fibrin plays a major role in stopping bleeding and healing wounds. However, if fibrin is formed in excess, e.g., in chronic wounds, thrombosis and subsequent vascular occlusions can occur. Therefore, ...

A group of researchers from the United States discovered that the spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can induce the formation of highly inflammatory ...

Drs. Castellarin, Fegan and Zarbin present an important case of the fibrinoid syndrome and its management. They not only review a case with typical findings, but also demonstrate that the syndrome can ...

When our blood vessels are injured by cuts, abrasions, or bruises, it is vital that the bleeding is stopped, and the wound is sealed. This process is called hemostasis and involves two main components ...

Fibrin was discovered 359 years ago. Its precursor, fibrinogen, is a fascinating and well-studied protein with unique properties. Increased fibrinogen levels have been shown to contribute to coronary ...