G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...
A number of membrane proteins that are present on the cell membrane control external and internal material transportation, cell protection and signal transmission. The diversity of functions of ...
Researchers used GPS-like tracking to observe how a key G protein-coupled receptor (GPCR) moves, revealing the core mechanism behind vital body functions. G protein-coupled receptors are embedded in ...
A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...
GPCRs are the largest receptor class, affecting almost every aspect of human physiology, with 35% of all approved drugs acting on GPCRs. They regulate sensory and neuronal signaling, as well as a ...
Researchers at Leipzig University and Martin Luther University Halle-Wittenberg have investigated a previously unknown ...
Researchers have shown that tolvaptan, an existing kidney medicine, can stabilise nearly all mutated variants of a critical ...
GLP-1 is a natural human hormone that regulates blood glucose levels. Scientists have now created long-lasting GLP-1 drugs ...
AbbVie is paying $255 million cash to acquire British biotech DJS Antibodies and its platform for targeting transmembrane proteins. DJS is focused on difficult-to-drug disease-causing proteins, such ...
From September 1, 2021, to March 23, 2022, 33 patients were infused with anti-GPRC5D CAR T cells. At a median follow-up of 5.2 months (range, 3.2‐8.9), the overall response rate was 91% (95% CI, 76 to ...