The kick-off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a ...

Microglia (immune cells) and the RANK protein are essential for triggering puberty and maintaining fertility in the brain.

Researchers found microglia influence reproductive hormone signaling through the RANK protein. The discovery links immune cells to puberty control and infertility, and may improve diagnosis and ...

Outside (left) and inside (right) of microglia cells interacting with GnRH neurons at spots (blue, left) where they engulf portions of GnRH neurons (lila, left). Top: mice from the control group.

Few topics provoke as much concern as the perception that puberty is beginning earlier than ever. While synthetic ...

The kick off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a hormone that activates the ...

In 1977, the Nobel Prize in Physiology or Medicine was awarded to Roger Guillemin and Andrew Schally for their discovery and synthesis of gonadotropin-releasing hormone (GnRH), a key regulator of ...