In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

A growing body of evidence indicates that studies utilizing organoids and microtissues yield more predictive and translational insights compared to traditional two-dimensional (2D) monolayer cell ...

Evaluating Anticancer Drugs and Building Tissue and Tumor Co-Culture Models Among Uses The need for new tools and technologies to decrease the cost of drug discovery and reduce animal testing has been ...

This article includes research findings that are yet to be peer-reviewed. Results are therefore regarded as preliminary and should be interpreted as such. Find out about the role of the peer review ...

Drastic differences in the ways cells behave and respond to drugs are observed when cells are cultured using 3D instead of 2D approaches. These differences are driving the adoption of more advanced ...

Cell invasion is a common characteristic of malignant cancers. This plays a central role in tumor metastasis and dissemination, and is largely responsible for deaths related to cancer (1, 2). Tumor ...

Three dimensional (3D) cell culture has been an area of increasing interest and relevance across a wide breadth of fields for some time now. One type of 3D structure generated in vitro are spheroids.