Iran fired a new wave of missile attacks on Israel early Monday, triggering air raid sirens across the country as emergency services reported at least five killed and dozens more wounded in the fourth day of open warfare between the regional foes that showed no sign of slowing.

Israel and Iran exchange missile attacks for a third day; nuclear sites hit, death tolls rise, airspace shut, U.S. warns Tehran against retaliation.

Nineteen Israelis have been reported killed in Iranian attacks since Friday, while Iran’s health ministry says 224 have died in Israeli strikes.

The missile and air war that Israel and Iran have spent decades planning for has come, and it is spectacular and terrifying. Israeli officials say they need at least two weeks to degrade Iran’s nuclear and missile capabilities.

Israel has launched a series of strikes against Iran, targeting the country’s nuclear program and other military infrastructure. Iran has launched its own strikes in retaliation.

It follows daytime attacks from both sides, with Israeli strikes in Tehran continuing and Iran firing more missiles towards Israel.

Israel hit more targets in Tehran and Iranian missiles fired at Israel killed at least 14, as the conflict entered a third day