Scientists have uncovered new genetic rules that determine whether the immune system’s “killer” T cells remain powerful long-term defenders or become worn out and ineffective. By building a detailed ...

Scientists in Brazil are refining the design of CAR-engineered immune cells to make them more precise and powerful against cancer.

Our immune system is great at fighting many types of cancer, but it struggles to see prostate tumors. While new treatments have been game-changers for lung cancer and skin cancer, prostate cancer ...

Active aldehydes drive T cell exhaustion in the tumor microenvironment This motivated a team of researchers from Kyoto University to investigate this conundrum. A key physiological role of FAO is the ...

Wistar Institute scientists have designed a two-vaccine approach that not only targets the tumors’ unique molecular identity ...

A UCLA research team has identified the best design for a promising new type of immunotherapy that could be mass-produced to treat multiple solid tumors. The study focused on engineered invariant ...

"Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body?" There are instances where killer T cells—which are meant to precisely remove virus-infected ...

A new study has uncovered new genetic rules that determine how CD8 “killer” T cells choose between becoming long-lasting, protective immune cells or slipping into exhausted, dysfunctional states.

When the immune system starts damaging healthy tissues, autoimmune diseases can develop. These conditions can affect many parts of the body, including the joints, bone marrow, skin, and organs.

A new study has revealed a promising new approach to curb the spread of triple-negative breast cancer, one of the most ...

Please provide your email address to receive an email when new articles are posted on . Allogeneic cell therapies help overcome challenges of autologous products, such as manufacturing complexity and ...