Aldosterone sends sodium and water into the bloodstream, which can increase your blood volume and blood pressure. Besides the ...

Late-breaking Phase 2 trial data evaluating the safety and efficacy of 25 mg of lorundrostat in participants with hypertension and comorbid CKD to be presented~~ Phase 3 data of the Launch-HTN Trial ...

A new drug aimed at treating primary aldosteronism—the most common but often overlooked cause of high blood pressure—is making waves in the medical community. But according to one of the world's top ...

Dr. Aaronson answers the question: 'What Is An Aldosterone Antagonist?' — -- Question: What is an aldosterone antagonist, how does it work, and when is it used to treat heart failure? Answer: ...

The emerging role of aldosterone in hypertension and cardiovascular diseases has prompted a renewal of interest in therapeutic approaches designed to interfere with the action of this ...

Elevated aldosterone levels may contribute to left ventricular (LV) structural remodeling post myocardial infarction (MI) and in patients with advanced heart failure, and aldosterone receptor blockade ...

A drug that has been used to slow progression of kidney and cardiovascular disease in people with type 2 diabetes may also help people with chronic kidney disease who do not have diabetes, according ...

The coronavirus disease 2019 (COVID-19) pandemic caused millions of deaths throughout the world, which has provoked intense research into the pathogenetic mechanism behind this disease. A new study ...

Type 2 diabetes (T2D) incidence continues to rise among African Americans (AAs). However, it has been observed to plateau among non-Hispanic whites (NHWs). Moreover, T2D-associated mortality and ...

Accumulating data indicate that ER stress may trigger autophagy. 11 Autophagy is a multi-step process of self-degradation of cellular components in which proteins and organelles are sequestered and ...