A series of experiments, with Secale cereale and Triticum aestivum var Argee, to evaluate critically the ability of a malate/aspartate shuttle to provide reducing equivalents to drive hydroxypyruvate ...

The requirement for metabolic efficiency forces cancer cells to generate sufficient energy equivalents to support their high proliferative activity. One cycle of glycolysis supplies cells with two ...

Background: Hyperthyroid induced cardiac hypertrophy is related to increased cardiac workload. These changes are associated with an upregulation of metabolic pathways associated with energy production ...

Citrin deficiency is an autosomal recessive disorder arising from mutations in the SLC25A13 gene. The deficiency impairs the mitochondrial aspartate–glutamate carrier, which is a key component of the ...

A new wave of scientific interest is spotlighting GOT2—glutamic-oxaloacetic transaminase 2—as a compelling therapeutic target in the fight against pancreatic cancer, one of the most lethal and ...