The formation of migrating cell clusters plays an important role in many biophysical processes, including cancer metastasis. In this work, we investigate how a potential cell-cell alignment mechanism ...

A new approach enables rapid characterization of living suspension cells in 4 dimensions while they are immobilized and manipulated within optical traps. Optical imaging of highly motile cells or ...

Exposure to second-hand tobacco smoke has been linked to numerous health problems, including poor wound healing, but the underlying molecular mechanisms have remained unclear. Research in the April 5 ...

Heterogeneity of epidermal growth factor receptor (EGFR) expression and variation in immunohistochemistry (IHC) testing may affect access to EGFR-targeted therapy in patients with advanced colorectal ...

This review illustrates how the nuclear phosphoinositide-p53 signalosome integrates lipid signaling and p53 function to regulate cancer cell motility. The figure contrasts the tumor-suppressive ...