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1. Gao Y, et al. Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells. Nat Immunol. 2017;18(9):1004-1015. 2. Sudholz H, et al. DOT1L maintains NK cell phenotype ...
Use mRNA electroporation to generate NK cells that express CD16-158V with minimal impact on cell survival and phenotype. Evaluate the effects of CD16-158V expression on rituximab-mediated ...
In this article, Sartorius discusses how their iQue® product can be used to examine donor and antibody diversity in NK cell-mediated ADCC through the use of multiplex assays and flow cytometry.
More information: Joanna Pozniak et al, Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype, Cancer Discovery (2025). DOI: 10.1158/2159 ...
Highlights: This study investigated the phenotype and function of GDA-201, NK cells expanded using Gamida Cell’s proprietary NAM technology.
WU-NK-101 cells possess a unique cytokine-induced memory-like (CIML) phenotype that supports enhanced anti-tumor activity, robust trafficking, superior proliferation capacity, and metabolic ...
Our K562-based feeder cell method results in consistent, robust expansion of highly-active clinical-grade NK cells that enables repeated delivery of large cell doses for improved efficacy. This ...
Highlights the unique therapeutic potential of Celularity clinical-stage candidate CYNK-001 in age-related diseasesFLORHAM PARK, N.J., April 07, 2025 (GLOBE NEWSWIRE) -- Celularity Inc. (Nasdaq ...