A novel mouse model offers definitive evidence that a single inhibitory receptor family governs the critical natural killer cell functions of licensing and missing-self.

Although traditionally classified as cells of the innate system, NK cells closely resemble T cells in phenotype and function. More recently NK cells have been thought to represent an evolutionary link ...

This study combines mathematical models and experimental data to analyse the emergence of heterogeneity within clonal NK cell responses during antigen-specific cell expansion. Although it comprises ...