A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, offering fresh insight into how human cells build and maintain chromatin, ...
The metabolism of nucleotides in plants is a fundamental process underpinning growth, development and adaptive responses to environmental cues. Central to these processes are the de novo synthesis and ...
Recent research from the lab of Dr. Nicolas Lehrbach, an Assistant Professor in the Basic Sciences Division at Fred Hutch, discovered that altering nucleotide metabolism may bypass proteasome defects ...
Researchers are able to test in parallel the effects of over 1500 active substances on cell metabolism. Their analysis also led to the discovery of previously unknown mechanisms for known medications.