After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, forms an abnormal connection with an enzyme called ClpP. This enzyme normally ...
Researchers have identified a key molecular interaction that accelerates Parkinson’s disease by damaging the brain’s energy ...
Ahmet Coskun's lab has developed iseqPLA to map protein interactions. An artistic rendering of sub-cellular activity: The cell membrane is seen at the top, nucleus on the bottom/right. Protein pairs ...
Researchers capture first-of-its-kind video of dynein–Lis1 protein interaction, supporting future drug development for neurological disorders. Our cells rely on microscopic highways and specialized ...
No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...
Proteins form the building blocks of life, but when they form unusual clumps inside the brain, they raise an alarm that something isn't right.
Scientists from Cleveland Clinic and Cornell University have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat ...
A team led by researchers at the University of Toronto has created a platform, called SIMPL2, that revolutionizes the study of protein-protein interactions by simplifying detection while improving ...
For 450 million years, plants and soil fungi have been trading partners. The fungi weave through plant roots, delivering ...
Results of thioflavin T fluorescence analyses revealed a drastic increase in the fluorescence intensity when BSA was mixed with ultra-small (10 nm) silica nanoparticles (NPs) with a stirring time of ...