To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...

A selective protein degradation system known as Golgi membrane-associated degradation (GOMED), which identifies and removes ...

Biological targets represent a considerable test of our knowledge of the fundamental principles of molecular recognition. Effective modulation of biological events requires the generation of molecules ...