Studies have demonstrated a critical role of the cytokines thymic stromal lymphopoietin (TSLP), IL-33, and IL-25, produced by epithelial and other cells at mucosal surfaces in response to a wide range ...

Ovarian cancer treatment faces challenges with high relapse and drug resistance rates, despite initial chemotherapy effectiveness. Cytokines like IL-6 and IL-11 are associated with complex tumor ...

Cytokines are secreted proteins critical for immune regulation, cell signaling, and tissue homeostasis. These cells are increasingly recognized as key tools in biomedical research, particularly in ...

Innate and adaptive immune cells coordinate the excessive inflammatory response known as a cytokine storm in acute respiratory distress syndrome, leading to alveolar–capillary barrier damage, ...

Researchers at Weill Cornell Medicine have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an ...

Cytokines contribute to the antitumor response through several key pathways and interactions with different immune cells. These include the following: (a) Natural killer (NK) cells: Cytokines such as ...

Cytokines play a central role in regulating physiological processes, largely because of their ability to orchestrate intercellular communication. As ...

Induced pluripotent stem cells (iPSCs) are a flexible source of tissue models for drug discovery, cancer research and disease modeling; however, differentiation of iPSCs into somatic tissues requires ...

Molecular biologists and biochemists these days are focusing an increasing share of their investigations on the activities of a class of small peptide messenger molecules called cytokines. The ...