Collaborating scientists at the Karolinska Institute and at Stockholm University used a technology called in situ sequencing (ISS) to help reveal at the cellular level how lesions in multiple ...

Chronic active lesions, which are identified by their darkened outer rims, are associated with more aggressive multiple sclerosis and earlier disability, according to new research from the National ...

Multiple sclerosis causes lesions to the spinal cord and other parts of the central nervous system. An MRI can detect spinal cord lesions and help diagnose and monitor the condition. Multiple ...

Even with disease-modifying therapies, patients who have chronically active inflammatory MS lesions can expect an aggressive disease course and poor outcomes. A new study shows that patients with ≥4 ...

Please provide your email address to receive an email when new articles are posted on . Researchers conducted a study of 431 adults with multiple sclerosis. Data showed lesion volume and damage were ...

Please provide your email address to receive an email when new articles are posted on . A phase 2 study included 129 individuals with MS randomized to receive frexalimab or placebo for 24 weeks.

The idea that multiple sclerosis is a disseminated plaque-like sclerosis was established approximately 150 years ago; indeed, the demonstration of dissemination — in space (disease-related changes in ...

Understanding the neurodegenerative processes involved in MS, particularly the role of white matter (WM) and grey matter (GM), may help clinicians to diagnose the disease earlier and maximize ...

We describe progressive multifocal leukoencephalopathy (PML) caused by infection with human polyomavirus JC virus in a patient with multiple sclerosis who was treated with natalizumab. The first PML ...