The high complexity and diversity of the eukaryotic transcriptome poses significant challenges for the efficient detection of specific transcripts. Conventional targeted RNA-seq methods often require ...

Table 1 Information on the current available S. acuminata transcriptomes. Three samples were used for library construction: vegetative cells at exponential growth stage, vegetative cells at stationary ...

The diagnosis of Mendelian conditions is challenged by the ability to detect pathogenic genetic variation accurately and to determine whether an identified genetic variant has a functional consequence ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

What makes a chili pepper spicy, colorful, and full of flavor? Scientists have now decoded the genetic journey behind pepper development, using long-read sequencing to build the most comprehensive ...

Now Shipping Kits for Technology that Brings Single-Cell Resolution to Most Common Archival Format Parse Biosciences, a QIAGEN company and the leading provider of scalable and accessible single-cell ...

The origin of many diseases begins at the cellular level and involves multiple molecular interactions. However, previous methods have struggled to accurately observe changes in individual cells.

Researchers increasingly turn to single-cell sequencing to answer a range of biological questions, with published single-cell data increasing year over year. As its popularity rises, so does the need ...

Immunology researchers are working to understand complex adaptive immune responses, but meaningful signals are often rare, transient, or difficult to capture across large, sample-limited studies.

Immunotherapy has been a revolutionary breakthrough for cancer therapeutics, but it is still hampered in that it only benefits certain patients. Moreover, the molecular determinants of immunotherapy ...

Peking University, August 18, 2025: A research team led by Professor Wang Yangming from the Institute of Molecular Medicine, College of Future Technology, and the Beijing Advanced Center of RNA ...