Nature

An improved transcriptome annotation reveals asymmetric expression and distinct regulation patterns in allotetraploid common carp

In allotetraploid common carp, protein-coding homoeologs presented divergent expression levels between the two subgenomes. However, whether subgenome dominance occurs in other transcriptional and post ...
Nature

De novo transcriptome assembly and annotation of the semi-wild Gayal (Bos frontalis)

The Gayal, also known as Mithun (Bos frontalis), is a rare semi-wild Bovine species found in the harsh environments of Indo-China 1,2. In China, the Gayal is predominantly located in the narrow ...
Phys.org

Simultaneously decoding the transcriptome, epigenome and 3D genome within a single cell

The origin of many diseases begins at the cellular level and involves multiple molecular interactions. However, previous methods have struggled to accurately observe changes in individual cells.
ascopubs.org

Cross-Comparison Individual Patient-Level Analysis of Three Gene Expression Signatures in Localized Prostate in Over 50,000 Men

Precision Treatment of Patients With GI Cancer Using Pre-emptive DPYD Genotyping/Phenotyping Plus Pharmacokinetic-Guided Dosing of 5-Fluorouracil Primary PCa biopsy samples underwent ...
ascopubs.org

Amivantamab treatment and intra-tumoral gene expression and immune cell changes in refractory metastatic colorectal cancer (mCRC): Whole transcriptome RNA-sequencing analysis ...

Outcomes of young-onset colorectal cancer vs late-onset colorectal cancer patients on phase 1 matched and non-matched therapies. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.