The No. 23 USC Trojans (5-1, 3-1 Big Ten) are back on the road after having its second bye week. They travel to Lincoln to face the Nebraska Cornhuskers (6-2, 3

Week 10 of the 2025 season is a pivotal point on the college football calendar. Not only does it mark the time at which almost every school in the nation will have played eight games -- or two-thirds of their schedule -- it also heralds the arrival of the first College Football Playoff rankings reveal.

College football Week 10 odds, picks, predictions, TV channel, streaming for USC Trojans vs Nebraska Cornhuskers Big Ten football game Nov. 1, 2025.

The No. 23 USC Trojans are 5-2 entering week 10 at the Nebraska Cornhuskers. With USC coming out of the loss to the No. 12 Notre Dame Fighting Irish, the Trojans face a must-win against Nebraska to keep their College Football Playoff Hopes alive.

The Rebels are 12.5-point favorites in the latest South Carolina vs. Ole Miss odds, while the over/under for total points scored is 55.5 via SportsLine consensus. Before making any Ole Miss vs. South Carolina picks,

No. 23 USC struggled through a miserable first half before it finally found its footing and did just enough to 21-17 win at Nebraska Saturday.

South Carolina fans have hit a boiling point after Saturday's loss, calling for the program to make a change at head coach across social media. "Shane Beamer needs to be fired for simply continuing to allow Mike Shula to call plays," one fan said.

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