Course TopicsPower analyses and sample size calculations are important parts of many research projects. Often, before data are even collected, it is necessary to calculate and justify the required ...

Course TopicsPower analyses and sample size calculations are important parts of many research projects. Often, before data are even collected, it is necessary to calculate and justify the required ...

In this article, we describe two tests for the case-cohort design, which can be treated as a natural generalization of log-rank test in the full cohort design. We derive an explicit form for ...

Statistical power and sample size are inextricably linked, with a positive correlation between power and sample size. An assortment of factors influences the power of a test including the sample size, ...

Vonesh and Schork (1986, Biometrics 42, 601-610) presented a statistical methodology for computing the minimum sample size required for the within-subjects repeated-measures design. They applied ...

Larger sample sizes not only increase the power of achieving trial objectives but also increase trial cost and duration. Despite flourishing literature in novel dose-finding designs, only a limited ...