Lewy body diseases -- Parkinson's disease and dementia with Lewy bodies -- should be defined as neuronal alpha-synuclein disease, not as clinical syndromes, a new position paper proposed. "Parkinson's ...

Parkinson's disease (PD) and dementia with Lewy bodies are currently defined by clinical features, which can be heterogeneous and do not capture the presymptomatic phase of neurodegeneration. Recent ...

Just as fluid biomarkers for amyloidosis and tau have revolutionized clinical studies of Alzheimer’s disease, α-synuclein markers are poised to do the same for Parkinson’s. With the advent of ...

Alberto J. Espay, MD, MSc, discusses a new biological definition of Parkinson's disease that is based on pathology identified through spinal fluid testing. The test uses the principles of ...

Parkinson’s disease is a neurodegenerative movement disorder that progresses relentlessly. It gradually impairs a person’s ability to function until they ultimately become immobile and often develop ...

Dear Savvy Senior: What are the early signs of Parkinson’s disease? My husband was recently diagnosed after noticing a slight thumb tremor, but we’re wondering if we missed any other early warning ...

Resting "pill-rolling" tremors are typical for Parkinson's disease. Other common symptoms of Parkinson's disease include stiffness, shuffling gait, slow movements, and changes to speech and writing.