The INO80 chromatin remodelling complex has various roles in genome maintenance, acting via nucleosome sliding and H2A.Z ...

What naked mole-rats lack in the looks department they make up for it in longevity, living healthily for nearly four decades.

Researchers at Spain’s CNIO have mapped 20,000 distinct DNA repair “scars,” building the first human REPAIRome. This atlas ...

The goal of gene therapy is to permanently cure hereditary diseases. One of the most promising technologies for this is the ...

The human repairome, REPAIRome, will allow researchers around the world to rapidly check out how each of the 20,000 human genes affects DNA repair. Created by researchers at the Spanish National ...

Significant advancements in gene silencing and gene editing offer new hope for treating rare disorders. Techniques like RNA ...

The clinical success of CRISPR-based treatments is fundamentally dependent on sophisticated gRNA targeting systems that ...

A study reveals the secrets behind the rodent’s remarkable ability to live 10 times longer than expected, without cancer or ...

These burrowing animals have a biological mechanism that does the opposite of what it does in humans: it repairs DNA instead ...

Faulty versions of the LMNA gene can cause a wide range of health problems, including heart muscle disease (dilated ...

The team genetically engineered fruit flies to make naked mole rat cGAS and found that they lived 70 days—10 days longer than ...

The research was also presented as an oral presentation at the Homology-Directed Repair ... edit double strand DNA, converting a cytosine (C) to a thymine (T) through the formation of an uracil (U) ...