RLM Health Foundation is on mission to combat cardiovascular disease through education, research, and community support, especially for underserved communities in St. Louis. Learn more ...

Members of the Edwardsville High School Athletic Hall of Fame Class of 2025 look back on their achievements during Friday's ...

The American Red Cross urges donors to give blood or platelets in February to help build up the blood supply after thousands ...

JEFFERSON CITY — The Missouri Board of Education on Tuesday approved the five-year renewals of charter schools Premier and ...

This will be our third local news team; this one will produce investigative, data and engagement journalism to serve ...

The Missouri Historical Society has launched the “We Are St. Louis” campaign, designed to introduce people to a St. Louis ...

Happy hour at 5 p.m., followed by the program at 6:30 p.m. 5 On Your Side’s Kelly Jackson and Brent Solomon will be there to ...

ST. LOUIS — A two-phase winter weather system is set to impact Missouri this week. St. Louis is in the transition zone, and that may have a significant impact on Wednesday’s snowfall forecast.

International Paper Co., a Tennessee-based paper company, announced Thursday that it plans to close four of its facilities, ...

Traci Carter, program manager of Raising St. Louis in Missouri, and Nicole Kozma, director of school and community outreach programs at St. Louis Children’s Hospital and BJC Community Health ...

Situated about halfway between Kansas City, Missouri, and Indianapolis, St. Louis overlooks the Mississippi River on the Missouri-Illinois border. Inside its 79 neighborhoods, visitors will find ...

STL Run Crew founder Ricky Hughes is looking to build a community and show people the mental benefits of running.