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San Francisco 49ers wide receiver Jauan Jennings can't hold on to a deep pass attempt from quarterback Mac Jones against the ...

Texans head coach DeMeco Ryans is a former 49ers defensive coordinator under Kyle Shanahan, so San Francisco knows how ...

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs.

But at halftime, the Texans led only 16-7 after San Francisco took advantage of former Alabama standout Brian Robinson Jr. ’s 46-yard kickoff return. With 25 seconds left in the first half, Jones ...

The redemption arc of quarterback Mac Jones was fun while it lasted, but the San Francisco 49ers need starting QB Brock Purdy ...

The 49ers had the ball for only 18 ½ minutes Sunday. It's an apt analogy for Mac Jones, whose time as San Francisco's ...

San Francisco 49ers QB Mac Jones fired a strike to WR Kendrick Bourne, moving the chains with an 18-yard gain vs. the Texans.

San Francisco 49ers TE George Kittle and QB Mac Jones showcased flashes of playmaking during the loss to Houston, highlighted ...

A week after the 49ers earned a 20-10 prime-time home win over the Atlanta Falcons, the Niners’ shorthanded defense was on ...