Analyzing Monday’s Jacksonville Jaguars at Buffalo Bills odds and lines, with expert NFL picks and predictions.

At 0-2, the Jaguars’ season is almost hanging in the balance already going into Week 3. And, a loss in Week 3 would be ...

The Jaguars average 4.0 fewer points per game (15.0) than the Bills allow (19.0). Jacksonville averages just 15.5 fewer yards ...

First, it was Tua Tagovailoa going down with a concussion in the Bills win last Thursday. Now, it's backup quarterback Skylar ...

Where does the Buffalo Bills' starting cornerback duo of Christian Benford and Rasul Douglas rank among the rest of the NFL?

Bills/Sabres owner Terry Pegula is thankful to have Guelli in place, and Guelli hopes this is the final stop of a journey ...

Also keep in mind that Buffalo has been one of the league’s best teams on both sides of the ball so far, ranking third in ...

Philadelphia Eagles LB Devin White has been named one of the NFL's top trade candidates, and the Buffalo Bills could be a ...

Buffalo Bills running back James Cook could be the key to the AFC East champs continuing their early season dominance.

After a disappointing start to the season, can the Jacksonville Jaguars' top pass catchers be trusted in fantasy lineups ...

Despite entering Sunday without a win to show for, Jacksonville has been much better than its record indicates. Find out why ...

ORCHARD PARK, N.Y. — The Buffalo Bills face the Jacksonville Jaguars for a week three matchup on Monday night. This game will be the Bills' first home primetime battle of the season. The Channel 2 ...