Inside a sprawling lab at the University of New England's Portland campus, scientists conduct research that could eventually lead to improved treatments for conditions that affect millions, including diabetes,

Of course the effects will vary across research institutions, as institutions differ markedly in their operating models and financial situations. Jobs will be lost, including faculty, trainees, and support staff.

For fiscal year 2023, NIH spent more than $35 billion in about 50,000 grants to more than 300,000 researchers at more than 2,500 medical schools, universities and other research institutions, the agency said, with about $9 billion of that going to indirect costs..