Compared to placebo (a sham medication), tirzepatide likely helps adults with obesity lose weight in the medium term (up to 2 years), and this weight reduction is likely to be maintained over the long ...

Liraglutide compared with placebo (a sham medication) likely increases the number of people who lose at least 5% of their body weight, but its impact on unwanted effects, quality of life, and major ...

Adults with obesity lose more weight with semaglutide than with placebo (a sham medication). However, the risk of unwanted events is probably higher than with placebo after 24 months. Semaglutide ...