AZoLifeSciences on MSN

Mapping the human E3 ligase landscape

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with precision.
So, what type of molecule is an enzyme? While the vast majority of enzymes are proteins, a small but important group, known as ribozymes, is made of RNA. Proteins are large molecules built from long ...
Reporting in Science, researchers at UC Santa Barbara, UCSF and the University of Pittsburgh have developed a new workflow for designing enzymes from scratch, paving the way toward more efficient, ...
Certain glycans -- sugar-like compounds with carbohydrate chains -- containing galactose, may exhibit potential prebiotic properties that support human health. Identifying enzymes capable of breaking ...
Enzymes are amazing catalysts. These proteins are made of nothing more than a handful of Earth-abundant elements, and they promote a vast array of reactions, convert chemical energy to physical motion ...
A new method that successfully designs serine hydrolase enzymes capable of catalyzing ester hydrolysis with high efficiency, demonstrates a computational approach for creating de novo enzymes that ...
Abstract: This study presents an innovative method for enzyme classification by integrating Exploratory Data Analysis (EDA) with a Neural Network (NN) framework. Utilizing a dataset of 858,777 ...
This Streamlit app provides an interface for exploratory data analysis (EDA) and prediction of EC1 and EC2 values using machine learning models. The app allows users to explore the dataset, visualize ...
This study reports important findings on identifying sequence motifs that predict substrate specificity in a class of lipid synthesis enzymes. It sheds light on a mechanism used by bacteria to modify ...