Microglia (immune cells) and the RANK protein are essential for triggering puberty and maintaining fertility in the brain.

The kick-off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a ...

Researchers found microglia influence reproductive hormone signaling through the RANK protein. The discovery links immune cells to puberty control and infertility, and may improve diagnosis and ...

Outside (left) and inside (right) of microglia cells interacting with GnRH neurons at spots (blue, left) where they engulf portions of GnRH neurons (lila, left). Top: mice from the control group.

Few topics provoke as much concern as the perception that puberty is beginning earlier than ever. While synthetic ...

In 1977, the Nobel Prize in Physiology or Medicine was awarded to Roger Guillemin and Andrew Schally for their discovery and synthesis of gonadotropin-releasing hormone (GnRH), a key regulator of ...

In the majority of IVF cycles, whether using an agonist or an antagonist protocol, the trigger used is human chorionic gonadotropin (hCG), which shares a common subunit with LH and thus acts as a ...

A recent study mapped the maternal brain from preconception through the crucial two years postpartum, illuminating how the brain reshapes itself during this pivotal life stage. “Mom brain,” that foggy ...