GLP-1 drugs like Ozempic and Wegovy aid in weight loss by suppressing appetite. Researchers are looking next at how the body expends energy – including through fat.

Can the bend of a banana give us insight into cancer? What does the shape of a rice grain have to do with infertility? The ...

Sepsis-associated liver injury (SALI) is a critical determinant of sepsis prognosis, characterized by extensive hepatocellular death and dysregulated immune responses. Emerging evidence highlights the ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

Five years ago, Nobel laureate Carolyn Bertozzi, PhD, and her team described novel small RNA-glycan conjugates, glycosylated RNAs (glycoRNAs), on the cell surface. These small non-coding RNAs have ...

This study investigates the function of Chi3l1 in hepatic macrophages in the context of MASLD, providing useful insights at a time when the distinct roles of Kupffer cells or monocyte-derived ...

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough ...

One of the main changes is a loss of the innate immune system's naive T cells, the first line of defense against pathogens, and an increase in the adaptive immune system's memory T cells. This ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. The manuscript ...

Chronic liver diseases (CLDs), encompassing a spectrum of etiologies including metabolic dysfunction, alcohol abuse, and viral infections, represent a significant global health burden. The progression ...

When damage to the liver caused by alcohol or viral infections persists, liver fibrosis progresses and replaces tissue with collagen fibers. This is especially a risk in chronic hepatitis C patients, ...

Please provide your email address to receive an email when new articles are posted on . A one-time infusion of BMS-986353, a CD19 CAR T-cell therapy, improved lung function and skin thickness.