Immunosuppressive medications. Drugs like corticosteroids or azathioprine work by calming the immune system and reducing the ...

Researchers create an artificial genetic system mimicking reverse translation, converting music into DNA to explore ...

Mutation Sprays are special gear in Grow a Garden that let players apply unique mutations to their crops. First introduced in the Crafters Update, some older sprays are no longer obtainable, but new ...

Resarchers targeted the genetics that underpin fruit elongation in domesticated cucumbers which are longer than their stubby, bitter tasting wild relatives. Cucumbers, a summer staple of salads and ...

Introduction: Wilson’s disease (hepatolenticular degeneration) is a common hereditary neurological disorder. Early diagnosis, particularly the widespread implementation of genetic testing and timely ...

Engineering of adeno-associated virus (AAV) replication proteins may provide new insights into Parvoviral replication. The authors created a useful collection of Rep protein variants with changes that ...

Transfection of AAV containing a K340H mutation in Rep. (A) To evaluate the activity of Rep, a K340H mutation was generated in the genome. Residue K340 directly interfaces with ATP in the helicase ...

If SpliceAI is able to identify the impact of such variants, this would be great, because usually synonymous alterations are filtered out of variant calling tools. Setting a manual filter for SpliceAI ...

Joshua L. C. Wong, Sophia David, Julia Sanchez-Garrido, Jia Z. Woo, Wen Wen Low, Fabio Morecchiato, Tommaso Giani, Gian Maria Rossolini, Konstantinos Beis, Stephen J ...

Abstract: Accurate identification of driver mutations is crucial in genetic studies of human cancers. While numerous cancer driver missense mutations have been identified, research into potential ...