Christian McCaffrey speaks out on the San Francisco 49ers’ mounting injury challenges after losing to the Houston Texans.

When the San Francisco 49ers finally picked up a first down Sunday against the Houston Texans they were already down by 16 ...

In Houston’s second offensive drive, rookie running back Woody Marks made another highlight-reel play. On second & 5, ...

Houston Texans defensive ends Danielle Hunter and Will Anderson Jr. drop San Francisco 49ers quarterback Mac Jones for a 10-yard loss on a sack.

San Francisco 49ers running back Christian McCaffrey hits a brutal juke on a 27-yard catch and run against the Houston Texans ...

The Texans arguably played one of their better games of the season and Houston's Week 8 report card reflects that.

The key is Jones beating the pass rush. The Houston defense is built around its front four getting pressure. Take that away ...

San Francisco 49ers CB Deommodore Lenoir picked off Houston Texans QB C.J. Stroud, marking the team's first interception of ...

San Francisco 49ers TE George Kittle made a strong grab in the end zone for a 17-yard touchdown against the Houston Texans.

At halftime, Houston held a 16-3 lead over the 5-2 49ers, as the Texans’ offense had outgained San Francisco 326 yards to ...

The Texans have dominated the 49ers, outgaining them 230 to 25 and outscoring them 13-0. The Texans have 10 first downs to ...