Porphyria - Causes, Symptoms, Diagnosis, Prevention, Treatment
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Code HAVIC @medschoolbro = Mystery Discount Acute Intermittent Porphyria (AIP) 🧩 Dx: AIP — porphobilinogen deaminase deficiency ⚡ Triggers: CYP-inducers (barbs, anti-seizures), fasting, alcohol, infections 🖐 5 P’s: Painful abdomen, Port-wine urine (darkens on standing), Polyneuropathy/paresthesias & weakness, Psych changes, Precipitated by drugs 🧪 Labs: ↑ ALA & PBG in urine; normal LFT/lipase/CT 💉 Tx (first-line): Hemin glucose → downregulates ALA-synthase 🚫 Avoid CYP inducers; stop offendi
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