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Cerebrospinal fluid (CSF) leaks are far more common in people with Ehlers-Danlos syndrome (EDS) than most realize. Because EDS affects connective tissue integrity, the dura mater—the protective layer that holds CSF—can be fragile and prone to tears. This can lead to spontaneous CSF leaks, often without trauma or medical procedures. When CSF pressure drops, the brain can sag, placing excessive strain on the brainstem and upper cervical spine. Over time, this can contribute to or worsen craniocerv
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